OV Therapy

OVs preferentially replicate within cancer cells and induce their death, while sparing healthy cells. They also infect tumor-associated endothelial cells, leading to breakdown of tumor vasculature and subsequent necrosis of uninfected tumor cells. In cancer cells, OVs rely on signaling pathways to establish infection and exploit defective anti-viral immune responsiveness to evade immune surveillance. The definition of “onco-lysis” is tumor destruction.

OV with cancer immunotherapy is a combined therapeutic approach.  The administered oncolytic virus (OV) attacks the cancer cells, leaving normal human cells untouched.  As a result this treatment has no significant side effects. Furthermore, OV combined with other therapies is a promising approach with potential to extend survival time and even cure, while quality of life is maintained. 

Dr. Sahinbas
Dr. Sahinbas is one of the leading European experts in hyperthermia, especially in the field of oncological therapies. He is a specialist in radiation medicine, radiology and palliative medicine. In addition to his practice, he works in a clinic as a radiologist and is president of the German Society for Hyperthermia. Dr. Sahinbas is a much sought-after speaker in national and international congresses. Above all, it is important for Dr. Sahinbas to ensure the best for his patients. Therefore he conducts research and advocates for the standardization of Hyperthermia in the treatment canon of health insurance companies.

Professional Title

Approbation as doctor: Witten Herdecke University – 1991
Specialist of Radiology- 2011
Specialist of Radiotherapy- 2014
Specialist of Palliative Medicine- 2017
Diploma in Complementary Medicine

Supervisory Authority:

Ärztekammer Nordrhein
Tersteegenstr. 9 · 40474 Düsseldorf
Tel. 0211 / 4302-0 · Fax 0211 / 4302 2009

Link to the Rules of Professional Practice:

Gesetze / Verordnungen – Ärztekammer Nordrhein (



Consulting Oncologist: Prof. Dr. med. Karl R. Aigner

Medical Director of the Medias Klinikum GmbH & Co KG, a private clinic for oncological surgery Read more

About us

The ATGesundheit Institute website presents information about oncolytic virus (OV) cancer immunotherapy for glioblastoma multiforme (GBM), solid tumors and breast cancer. Our website is dedicated to exploring the therapeutic potential of OVs for incurable tumors and the therapeutic mechanisms of various OVs.

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